Probio7 Targeted Immunity | AB21 Gut

Targeted Immune Support
2 years+

A box of Probio7 Targeted Immunity Probiotics stands upright on stacked natural stones against a muted green background.

Targeted Immunity powered by AB21 formula | Gut-Lung axis & Immune Support

Probio7 Targeted Immunity is a precision probiotic formula combining four carefully selected bacterial strains in the clinically studied AB21 blend, developed through research into the connection between the gut microbiome and immune system.

Each capsule contains 2 billion live bacteria, plus added vitamin D to support normal immune function.

Four targeted strains. One researched formula. Everyday immune support.

*Probio7 AB21 has become Targeted Immunity. You may receive AB21 or Targeted Immunity packaging during the transition, but the trusted, clinically proven formula remains unchanged.

£22.99

2 billion live bacteria per capsule
4 specifically selected bacterial strains
Vitamin D3 helps support immune function
AB21 formula studied in adult and children clinical trials

Free UK shipping

Pair Probio7 Targeted Immunity with FibreKind for a complementary approach to your daily gut health routine.

While Targeted Immunity contains four specifically selected live bacterial strains from the researched AB21 formula, FibreKind provides a blend of four dietary fibres, including acacia gum and partially hydrolysed guar gum (PHGG).

Together, they bring live bacteria and fibre into your everyday routine, helping you care for your gut in harmony.

SHOP HERE

Enjoy 30% off our new Fibre Kind – limited-time introductory offer.

Take one capsule daily with breakfast.

Capsules can be swallowed whole or opened and mixed into cold food or a cold drink.

Suitable for adults and children aged 2 years and over, subject to the approved pack directions.

Do not exceed the recommended daily intake. Food supplements should not replace a varied, balanced diet and healthy lifestyle.

Each capsule contains: Maltodextrin, Vegetable Capsule Shell, Lactiplantibacillus plantarum KABP™022, Lactiplantibacillus plantarum KABP™023, Pediococcus acidilactici KABP™021, Lactiplantibacillus plantarum KABP™033, Vitamin D3 (Cholecalciferol), Magnesium Stearate.

Allergy Advice: None.

Those wishing to enhance the body’s natural defences against respiratory tract infections, particularly those caused by viruses.
Adults interested in respiratory health. The AB21 formula used in Targeted Immunity was investigated in a 30-day clinical trial involving 300 adults aged 18–60 with COVID-19.
Children aged two years and over, needing support against respiratory tract infections. A 15-day clinical trial was conducted with 75 children aged 6 months to 5 years.
Those interested in the gut–lung axis. The science of how the gut, immune system and lungs communicate with one another.

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Four specifically selected live bacterial strains
Added vitamin D3 for normal immune function
Blend investigated in two published human clinical studies
Suitable for vegetarians
2 billion live bacteria per capsule

THE SCIENCE BEHIND TARGETED IMMUNITY

One targeted formula. Two published human clinical studies.

The AB21 four-strain formula has been investigated in two randomised, placebo-controlled human clinical trials involving adults and young children looking at markers of immune response and respiratory health.

Sources: Gutiérrez-Castrellón et al. (2022), Gut Microbes; Andrade-Platas et al. (2025), European Journal of Pediatrics.

What the clinical studies found

Results from two published human clinical studies showed significant benefits for respiratory health

An infographic titled 'ADULT STUDY' with teal icons and text on a white background, reporting results from a 30-day COVID-19 trial: 300 adults aged 18-60, median duration 5 days shorter than placebo, and 53% complete symptom and viral remission by day 30.

An infographic titled 'CHILDREN STUDY' with text about a 15-day trial of 75 children aged 6 months to 5 years with upper respiratory infections and pharyngitis. It shows two comparison points: '1.

A stylized medical illustration showing the lungs above the intestines with arrows circling around them, rendered in teal, blue, and yellow on a very light gray background.

A natural connection between your gut and lungs

Did you know your gut and lungs communicate with each other?

Your gut is home to trillions of microorganisms that interact with your immune system. This two-way communication between your gut and respiratory system is known as the gut–lung axis.

The four strains in AB21 have been researched for their interactions with three key processes:

Immune system communication: The bacteria in your gut can communicate with immune cells, which play an important role in your body's natural defences. AB21's strains have been studied for how they interact with these cells.
Your gut's protective barrier: Think of your gut lining as a protective wall, helping keep unwanted substances out of your bloodstream. Researchers have investigated how substances produced by AB21's bacteria interact with this barrier.
Keeping inflammation in balance: Inflammation is a natural part of your body's defence system, but it's important that the response stays balanced. Research into AB21 has explored how its bacteria produce substances involved in regulating inflammatory signals.

Four circular grayscale micrographs of bacteria arranged on a pale blue background, each labeled with a species name and code, including Pediococcus acidilactici KABP®O21, Lactiplantibacillus plantarum KABP®O23, Lactiplantibacillus plantarum KABP®O22, and Lactiplantibacillus plantarum KABP®O33.

A unique formula, backed by research

Targeted Immunity's AB21 formula contains a patented blend of four specifically selected live bacterial strains, investigated together as a complete formula in published human clinical studies.

Each strain has its own unique properties:

Lactiplantibacillus plantarum KABP™033 — Immune communication: Studied for how it interacts with immune cells involved in the body's natural defences.
Lactiplantibacillus plantarum KABP™022 — Gut barrier: Researched for compounds involved in maintaining the gut's protective lining.
Lactiplantibacillus plantarum KABP™023 — Inflammatory response: Investigated for its production of compounds involved in regulating inflammation.
Pediococcus acidilactici KABP™021 — Gut environment: Studied for its production of acetate, a naturally occurring compound involved in gut health research.

Your questions answered

AB21 is the name of the scientifically researched four-strain bacterial formula used in Probio7 Targeted Immunity.

Targeted Immunity is our product name, while AB21 identifies the specific combination of bacterial strains behind the science.

It's the same researched AB21 bacterial formula, brought to you by Probio7 with added vitamin D3 for normal immune function.

The gut–lung axis describes the two-way communication between your gut microbiome, immune system and respiratory system.

Gut bacteria interact with immune cells and produce compounds that may influence immune activity elsewhere in the body, including the lungs.

Scientists are continuing to investigate this relationship and its importance for human health.

Yes, Probio7 Targeted Immunity is suitable for children aged 2 years and over.

The AB21 formula has also been investigated in a clinical study involving 75 children aged 6 months to 5 years with upper respiratory infections, measuring how many days fever and discomfort lasted. In that study, children took the formula twice daily for 15 days.

For children aged 2 years and over, follow the recommended daily dosage on the packaging. If you're unsure, speak to a healthcare professional before use.

To book a 1:1 consultation with our in-house nutritionist. CLICK HERE

Vitamin D contributes to the normal function of the immune system and helps maintain normal bone and muscle function.

It provides additional nutritional support alongside the four bacterial strains.

You can generally take live bacteria supplements alongside antibiotics, but we recommend leaving 2–4 hours between your antibiotic dose and Targeted Immunity.

Always follow the advice of your doctor or pharmacist.

No. Targeted Immunity does not require refrigeration. Store it according to the instructions on the packaging, away from excess heat and moisture.

Targeted Immunity contains a specialised four-strain bacterial formula. This formula, AB21, has been investigated in human clinical trials in adults and children, looking specifically at the gut-lung axis. It is this targeted approach that makes it different from our broader everyday live bacteria formulas.

“Very seldom do I succumb to coughs and colds when taking this in spite of spending a lot of time with young grandchildren. Also have good resistance to Covid and if I do contract it have very mild symptoms.”

AB21

David

“I've had Probio7 supplements before, after antibiotics, however I chose this particular one as I'm susceptible to chest infections and had covid.”

AB21

Aron

Targeted Immunity powered by AB21 formula | Gut-Lung axis & Immune Support

One targeted formula. Two published human clinical studies.

What the clinical studies found

A natural connection between your gut and lungs

A unique formula, backed by research

Your questions answered

Expert opinion

Sally Spicer, Head of Nutrition

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Targeted Immunity powered by AB21 formula | Gut-Lung axis & Immune Support

One targeted formula. Two published human clinical studies.

What the clinical studies found

A natural connection between your gut and lungs

A unique formula, backed by research

Get the bundle & Save 20%

Targeted Immunity powered by AB21 formula | Gut-Lung axis & Immune Support

Advanced – High Strength Support

Expert opinion

Sally Spicer, Head of Nutrition

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