Published in https://journals.lww.com - Efficacy of a probiotic formula in the management of menopausal symptoms and quality of life: a randomised controlled trial
The Gut–Menopause Connection
More than 80% of women experience menopause symptoms such as hot flushes, mood changes, poor sleep and reduced libido, often linked to falling oestrogen levels.
But menopause does not only affect hormones — it can also influence the gut microbiome. A group of gut bacteria known as the estrobolome helps play a role in how oestrogen is processed and reabsorbed in the body.
This connection between the gut microbiome and oestrogen metabolism is often called the gut–oestrogen axis. Probio7 Menopause is formulated with 3 scientifically studied live bacteria strains to support this daily gut–hormone connection through menopause.
3 scientifically studied live strains
Probio7 Menopause contains 1 billion live bacteria from three carefully selected strains, clinically studied in peri- and postmenopausal women.
- Lactobacillus brevis KABP™052
Supports the natural recycling of oestrogen in the gut, helping support the gut–oestrogen connection during menopause. - Lactobacillus plantarum KABP™051
Supports the production of beneficial compounds within the gut and helps maintain a healthy microbiome. - Pediococcus acidilactici KABP™021
Helps support the gut barrier and digestive health.
Taken daily, these strains are designed to work together as part of a targeted menopause routine.
More than live bacteria
Alongside the three clinically studied bacterial strains, Probio7 Menopause also contains vitamin B6, vitamin D and folic acid to support women’s everyday wellbeing during menopause.
- Vitamin B6 contributes to the regulation of hormonal activity, normal energy-yielding metabolism, normal psychological function, and the reduction of tiredness and fatigue.
- Vitamin D contributes to the maintenance of normal bones, muscle function and immune system function.
- Folate / folic acid contributes to normal psychological function and the reduction of tiredness and fatigue.
FAQs
It’s made for women going through perimenopause and menopause and want targeted, natural support. Whether you’re dealing with hot flushes, mood changes, or disrupted sleep, this formula eases the ride by supporting hormone balance.
This is precision-formulated. With three specific live bacteria strains plus folic acid, vitamin B6, and vitamin D, it targets both gut and hormone health. It’s a probiotic clinically shown to modulate hormone levels which can improve menopause symptoms, like mood, sleep, and hot flushes.
Start as soon as you notice change, irregular periods, night sweats, mood swings or energy dips. Take one capsule daily with breakfast and for best results, use it consistently for at least three months. It’s safe and gentle for long-term use too.
If you’re pregnant, breastfeeding, taking medication, or have a medical condition, please check with your GP before use.
- Lactobacillus brevis KABP-052, helps the body recycle oestrogen in the gut, supporting more balanced levels through menopause.
- Lactobacillus plantarum KABP-051, supports the gut in making beneficial compounds, linked to immune and metabolic support during menopause.
- Pediococcus acidilactici KABP-021, helps support a strong gut lining, reinforcing the gut’s natural protective barrier.
The gut–oestrogen axis describes the two-way relationship between the gut microbiome and oestrogen. Certain gut bacteria can influence how oestrogen is processed and recycled in the body, while oestrogen can also affect the composition and function of the gut microbiome.
Probio7 Menopause contains three specifically selected strains: Levilactobacillus brevis KABP™052 (formerly known as Lactobacillus brevis), Lactiplantibacillus plantarum KABP™051 (formerly known as Lactobacillus plantarum), Pediococcus acidilactici KABP™021.
In laboratory (in vitro) screening of 84 bacterial strains, Levilactobacillus brevis KABP™052 showed the highest activity of an enzyme called β-glucuronidase (GUS) among the strains selected for further testing. This is significant because β-glucuronidase (GUS) is an enzyme involved in the way oestrogen is processed in the gut.
Some gut bacteria produce this enzyme, which can help convert oestrogen into a form that may be reabsorbed back into the bloodstream rather than simply being removed from the body. Levilactobacillus brevis KABP™052 stood out because it showed the strongest activity of an enzyme linked to the gut–oestrogen pathway.
That makes it especially interesting for menopause research, when oestrogen levels are naturally changing.
Yes. The same three-strain formula used in Probio7 Menopause has been studied in randomised, double-blind, placebo-controlled trials in peri- and postmenopausal women.
No. Probio7 Menopause does not contain oestrogen or other hormones. It contains three live bacterial strains, together with vitamin B6, vitamin D and folic acid.
Recently viewed
You may also like
